You will find here examples of people who suffered severe toxic reactions to 5-FU chemotherapy treatment. Pre-screening for DPD deficiency could have averted the problems these individuals endured. The type of pre-screening does matter: In the case of Linda here, her family had her tested for the DPD deficiency, post-mortem, but found no genetic deficiency. The type of "functional", not genetic, test performed by Dr. Ciccolini (see Hope) may have been useful in helping Linda avoid the toxic reaction and suffering stemming from her treatment.
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